The correct way to store vaccines is

Correct preservation methods of vaccines.

First of all, let's talk about the classification of vaccines:

Vaccines can generally be divided into two types, inactivated vaccine and attenuated live vaccine. According to the dosage form, it can be divided into two modes: vaccine diluent integration and vaccine diluent storage alone. Generally speaking, inactivated vaccines are often integrated, and live vaccines are often stored separately.

Vaccine preservation methods can generally be divided into fresh-keeping preservation (2-8) and frozen preservation (below-15). Generally speaking, inactivated vaccines are fresh-keeping and live vaccines are frozen. Nowadays, with the progress of science and technology and the application of heat-resistant protective agents for vaccines, many manufacturers also adopt preservation methods for live vaccines, such as Shuoteng animal protection.

For inactivated vaccine, because the vaccine is inactive, it is not sensitive to temperature requirements. However, for live vaccines, the most important thing to pay attention to when storing vaccines is temperature. The lower the temperature, the worse the life activity of the vaccine, and the division and reproduction of the vaccine will be in a static state, thus keeping the activity of the vaccine for a longer time.

Therefore, it is very necessary to preserve the vaccine in strict accordance with the instructions.

However, we will inevitably put the vaccine in the wrong place. There are four main situations here.

Situation 1: Inactivated vaccines that should be kept fresh are frozen.

A: The vaccine that should be kept fresh is generally a liquid mixed with vaccine diluent. Generally, many other ingredients are added to this liquid, which is easy to form vaccine stratification after freezing, resulting in a decline in effect.

Situation 2: Live vaccines that should have been frozen are kept fresh.

A: This problem is generally not too big, but it will affect the storage time of vaccines. If it is kept for a short time, it is not a big problem to take it out for use, but if it is kept for a long time (more than 3 weeks), it is best not to use it, so as not to affect the effect.

Case 3: Freeze-dried powder and diluent that should be kept fresh at the same time.

If freeze-dried powder and diluent are frozen together, the effect may not be as good as that of freeze-dried powder alone, but it will still be used, but the effect will be discounted.

Situation 4: Freeze-dried live vaccine which should be kept fresh is frozen.

A: If it's just freeze-dried powder, congratulations, it's not a big problem. What you need to do is to keep the temperature of freeze-dried powder and diluent the same before use.

Here, we need to pay attention to a problem: some people mix frozen freeze-dried powder with diluent immediately after taking it out, so if it is winter, the impact may not be great, but if it is summer, the temperature of diluent placed indoors reaches more than 30 degrees, and the temperature of freeze-dried powder vaccine just taken out is MINUS 15 degrees. The huge temperature difference of 40 to 50 degrees will seriously damage the structure and activity of the vaccine, thus causing artificial damage to the vaccine.