I have an American work visa. Can mom apply for a tourist visa to live in the United States for a long time?

First, your mother can apply for a tourist visa. But whether 100% can apply successfully, no one can give you this guarantee. I have seen some netizens, especially those who already hold green cards or are citizens, being repeatedly blocked when applying for visiting relatives in the United States for their widowed father or mother. Also, even if your mother's application for visiting relatives is successful, as you said, it is not so feasible to apply again immediately after returning to China. Most netizens will advise the elderly to stay in China for a period of time before applying to visit relatives in the United States. Your filial piety is very touching, but you and your mother must face the reality and summon up courage to face the future life. Besides, if your mother can't speak that language and drive, she may not be as happy as you think in America. Besides, you must find a girlfriend to get married. If your mother can't get out of the shadow of divorce and is ready to rely on you all the time, I'm afraid neither you nor she will be very happy. I sincerely hope that you will get the ideal career development opportunity and arrange your life with your mother. Good luck.