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What difficulties should be solved in building a permanent residence on the moon?

1. First of all, the most important thing is to solve the problem of water and oxygen:

2. Because the moon has no atmosphere, a lot of cosmic radiation will affect people's health, which is also a problem that needs to be solved;

The gravity of the moon is one sixth of that of the earth. In this case, in order to solve the problem of weightlessness,

The temperature difference between day and night of the moon is also great, and its lowest and highest temperatures are beyond the range that human beings can bear. This problem should also be solved.

I hope it helps you.