Is it okay to sign Macao twice for Hong Kong and Macao Pass?

Yes, take the tourist visa as an example:

Endorsement for visiting relatives (T).

Those who visit their spouses, parents or their parents, children or their spouses may issue multiple endorsements for three months and stay in Hong Kong or Macao for no more than 90 days from the date of first entry. Applicants over 60 years of age (inclusive) may issue multiple endorsements 1 year, and each stay in Hong Kong or Macao shall not exceed 90 days.

Those who apply to visit their spouses in Hong Kong and Macao and have minor children with their spouses in Hong Kong and Macao may issue multiple endorsements 1 year, and stay in Hong Kong or Macao for no more than 90 days at a time.

If the family is in special difficulties, with the approval of the exit-entry administration department of the provincial public security organ, it can issue multiple endorsements of 1 year, and each stay in Hong Kong or Macao shall not exceed 90 days.

The accompanying applicant can issue a visit endorsement with the same validity period and valid times as the main applicant.

Therefore, you can apply for multiple visas for three months, which means that you can travel to and from Macao multiple times within three months.

Extended data

Application conditions

Mainland residents can apply for travel permits to and from Hong Kong and Macao respectively according to their needs. Mainland residents who apply for travel permits and endorsements to and from Hong Kong and Macao at the same time, or apply for endorsements separately with valid travel permits to and from Hong Kong and Macao, must meet the corresponding conditions according to different reasons:

Visiting relatives: visiting relatives who have settled, lived, studied or worked in Hong Kong or Macao for a long time; The applicant's spouse and children under the age of 18 can apply together. "Relatives" refer to spouses, parents or parents of spouses, spouses, brothers and sisters, (foreign) grandparents and (foreign) grandchildren of children; "Accompanying application" refers to the application for visiting relatives with the same validity period and number of times as the main applicant.

Government Service Platform of National Immigration Bureau-Guide for Issuing Pass and Endorsement to and from Hong Kong and Macao