During the Ming Dynasty, did China people do business in Europe?

Maybe some people have it, but it seems that it has never been recorded. On the one hand, merchants in Ming Dynasty had no social status, so there were not many records about their deeds. On the other hand, it will take at least a few years to travel halfway across the world from China to Europe. If it was for business, Europe had colonies in Southeast Asia at that time, and trading there seemed more convenient and less risky.

In addition, those people mentioned upstairs are basically envoys who seek dharma/preach or are sent by the government. There are basically no businessmen. Because it's one thing to arrive in Europe from China, it's quite another to transport a lot of goods from China or Europe to Europe or China.