How to eat Australian probiotic lifespace

Conclusion: Taking probiotics may be risky, only under special circumstances. The probability of occurrence is very low, but it is still worthy of our attention.

In short, two types of people may be at risk of infection when taking probiotics:

1, severely immunocompromised and immunocompromised

2. People with intestinal barrier problems

Immune deficiency patients, premature infants, patients with short bowel syndrome, patients with central venous catheter, elderly patients, patients with congenital heart disease and heart valve disease, patients in the recovery period of intestinal surgery, patients with malignant tumors and patients with ascites due to liver cirrhosis, please use probiotic products with caution, and it is recommended not to take them.

Safety evaluation of probiotics.

When it comes to who is not suitable for taking probiotics, we are actually talking about the safety of probiotics.

We humans have a long history of eating bacteria. Our common probiotics (Lactobacillus and Bifidobacterium) are recognized as safe food (GRAS). GRAS is an index for FDA to evaluate the safety of food additives. The strains in the List of Edible Fungi Species published in China are all within the scope of GRAS, so probiotics are generally considered to be safe.

As a manufacturer of probiotics, before the listing of probiotics, in order to ensure that everyone will not be poisoned, the relevant safety assessment was carried out.

So what screening criteria should probiotics have? (Fu Xiao bacteria have passed these layers of screening! ) introduction:

The source of 1. strain should be healthy intestine and traditional fermented food.

2. Identification of strains (pathogenic genes)

3. Analysis of harmful metabolites: including endotoxin, hemolysin, nitrite, D- lactic acid, biogenic amines, aromatic amines and other substances.

4. Antibiotic tolerance: Antibiotic-free tolerance is an increasingly important indicator, mainly to prevent the emergence of superbugs.

5. Adhesion: Adhesion is an important indicator for probiotics to function, which is controversial, but some scholars believe that excessive adhesion may increase the pathogenic risk of probiotics.

6. Allergic reaction

7. Bile salt dissociation and gastrointestinal mucosa exfoliation

8. Animal experiment: acute toxicity experiment; Chronic toxicity test; Reproductive toxicity test

9. Human trials.

2. Side effects of probiotics

Therefore, a lot of experiments were done before probiotics went on the market to ensure that everyone had no problem eating them. Isn't it safe to sit down and relax?

Actually, it is not.

In some cases, probiotics may still have side effects on some special people!

The main problem is still focused on "infectivity", that is, whether probiotics enter the blood will cause sepsis or other related diseases.

Unfortunately, although our probiotics are basically tested for infectivity through animal experiments, there are still many probiotics that may be related to Lactobacillus and Bifidobacterium. Or other local or systemic infections, such as endocarditis and septicemia related to lactic acid bacteria intake.

3. What kind of people are not suitable for taking probiotics?

Well, after reading so many cases, did it scare you to death? I dare not eat at all! !

Don't worry, in fact, if you look carefully, these cases are special people!

Simply put, there are two kinds of people:

? 1, severely immunocompromised and immunocompromised

? 2. People with intestinal barrier problems

These two groups of people need to be careful when taking probiotics. My suggestion is that it is best not to take it, because it is really difficult for ordinary people to tell whether these two situations are true or false. In fact, according to the current statistics, the infection probability of probiotics for this group of people is so low that many scholars think that these side effects are sporadic.

Which groups are not recommended to take it?

Immunodeficiency patients, premature infants, patients with short bowel syndrome, patients with central venous catheter, elderly patients, patients with congenital heart disease and heart valve disease, patients with intestinal surgery in convalescence, patients with malignant tumors, patients with severe inflammatory bowel disease, and patients with ascites due to cirrhosis.

Don't worry too much, most people can eat it.

In fact, we really don't have to panic about the side effects of probiotics, because according to the current data, the infectivity of probiotics can be summarized as follows:

1. At present, all clinical infection cases involving lactic acid bacteria come from the sick people, especially those with impaired immune system.

2. No infection cases related to lactic acid bacteria were observed in healthy people or pregnant women.

3. Compared with the normal population, no more lactic acid bacteria-related infections were observed in the population exposed to high doses of lactic acid bacteria for a long time.

4. At present, no infection cases caused by eating fermented food, probiotics or drugs containing probiotics under normal circumstances have been found.

5. The infectivity of probiotics is related to strains, and not all strains are highly contagious.

Therefore, unlike the two special groups mentioned above, most probiotic products (several of which will be explained in detail next time) can be used with confidence. Don't be frightened by the article. These are extremely special circumstances.