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Pfizer paciclovir, as one of the oral drugs approved by COVID-19, has attracted much attention from consumers. On February 28th, the reporter of 65438 Times Weekly was informed that the Internet Hospital of Medical Union limited the daily supply of Pfizer paciclovir, and the product price was 2980 yuan/box.
On the same day, the Medical Association told Time Weekly that the timing of using paciclovir was within 5 days after symptoms appeared. At present, due to the shortage of antigen self-test time and medical resources, some patients missed the best virus blocking period. Internet hospital is not limited by time and space and has high accessibility, which can solve this problem well.
According to the data, paciclovir is an oral small molecule COVID-19 drug developed by Huirui Company, which is used to treat adult patients with mild to moderate novel coronavirus infection and severe high-risk factors, including the elderly, chronic kidney disease, diabetes, cardiovascular disease, chronic lung disease and other severe high-risk factors.
In February 2022, the State Administration of Medical Products conditionally approved the import of paciclovir. On March 15, paciclovir was included in the treatment plan of novel coronavirus. On February 7th, 65438, the epidemic prevention and control in China entered a new stage, and consumers' concern and demand for "specific drugs" in COVID-19 continued to rise.
Paxlovid is put on the shelves of medical associations, giving priority to high-risk groups.
According to the introduction of the medical association, Paxlovid is currently available in limited quantities on the platform of the medical association. Based on the medication guidelines, priority will be given to high-risk groups, including the elderly over 65 years old, patients with basic diseases and unvaccinated people. The above-mentioned patients are required to provide relevant identification certificates at the time of seeing a doctor to ensure that drugs can be accurately supplied to these groups.
It is reported that the medical association has invited experts to carry out medication training for platform doctors and formulate relevant SOPs to ensure that patients who meet the indications of the drug can be accurately identified through strict consultation procedures. At the same time, coordinate resources and give priority to express delivery of drugs to patients.
Different from the e-commerce platform, "Medical Internet Hospital is a professional platform with strict online prescription qualifications. According to the Notice on Doing a Good Job in Internet Medical Services in COVID-19 issued by National Health Commission, we provide online diagnosis and treatment and prescription purchase for patients through Internet hospitals in time. Medical services. " The medical association said.
65438+February 28th 1 1, the reporter of Time Weekly scanned the QR code of the poster of the medical association, filled in the basic information, allergy history, past medical history, pregnancy preparation and other contents, and then logged into the Internet Hospital of the medical association. In the Paxlovid product interface, click "Ask a doctor to prescribe medicine", and the system will prompt "Today's limit is full, please try to buy it today 18: 00, thanks for understanding!"
Image source: screenshot of mobile phone
The Medical Union Internet Hospital was established on 20 14. According to official website, the company's disease management services have covered diseases such as tumor, cardiovascular and cerebrovascular diseases, diabetes, chronic kidney disease, infection, psychology, gynecology, dermatology, gastroenterology, neurology, traditional Chinese medicine, etc., and created a team of medical assistants and health managers to empower doctors and serve patients.
Some insiders told Time Weekly that the current epidemic prevention and control in China has entered a new stage. As an important supplementary channel of offline clinics, Internet hospitals can reduce cross-infection caused by patients concentrated in hospitals. However, online consultation needs strict control, and the boundary between online consultation and online sales needs to be clarified.
Some hospitals provide limited amounts for cancer patients, and Beijing medical insurance can reimburse them.
At present, hospitals are still the main channels for purchasing paciclovir. Earlier, some media said that the fever clinic of Guangzhou United Family Hospital provided paxillovir, but the consultation fee for making an appointment with a doctor in the fever clinic was close to 1.300 yuan. Around related issues, Time Weekly reporters called a number of United Family Hospitals.
Guangzhou Hejia Hospital said, "The fever clinic needs an appointment, and the doctor can prescribe medicine according to the patient's condition; Moreover, due to the limited number of drugs, depending on whether there are drugs at the time of treatment, there is no guarantee that the treatment will be open to paciclovir. "
The official telephone of Shanghai United Family Hospital suggested that "COVID-19 oral medicine in the hospital is currently out of stock." The official telephone message of Beijing United Family Hospital said, "Due to the extremely limited inventory, our hospital cannot accept customers who open paciclovir in COVID-19. If you feel unwell, please make an appointment in time. "
The service number 65438 of Beijing United Family Hospital issued a document on February 28th, saying, "From now on, Beijing United Family Dongcheng Hospital will provide limited amount of paciclovir for cancer patients who meet the medication requirements, and cancer patients who have registered with United Family MRN will be given priority in line."
Previously, the "Emergency Notice on Organizing the Training of Medical Staff in Community Health Service Institutions in the City" was circulated on the Internet, saying that paciclovir would be distributed to the Beijing Community Health Service Center, and community doctors would instruct COVID-19 patients to take it for antiviral treatment. At the same time, Beijing will organize emergency training for community doctors in the city on the application of antiviral drugs.
On February 28th, 65438, the staff of a community health service center in Xicheng District of Beijing confirmed the above training to the reporter of Time Weekly. The training content is mainly medication, but the community hospital to which it belongs has not received the sent paciclovir.
According to him, according to the training requirements, the prescription requires a clinical diagnosis certificate to confirm COVID-19 infection, and it should be used five days before onset. However, the specific prescription process and whether to enter medical insurance are not clear. "I haven't received any other detailed notice except training," said the staff.
Subsequently, the reporter of Time Weekly called the Beijing Medical Insurance Bureau, and the relevant person in charge confirmed that the price of paciclovir was 2,300 yuan/box, which has been included in the list of medical insurance drugs in Beijing, that is, included in the scope of reimbursement, but it is necessary to pay attention to the hospital level, outpatient deductible line and capping line.
Expert: The best effect is to take it within 72 hours after infection.
On February 1 1, 2022, the State Administration of Pharmaceutical Products approved the import registration of Pfizer COVID-19's therapeutic drug paciclovir according to the special drug approval procedures. Paxlovid is approved for the treatment of adult patients with mild to moderate COVID-19's disease, which has a high risk factor for progression to severe disease. The initial price is 2,300 yuan/box.
On March 15, Paciclovir was included in the diagnosis and treatment plan and used as a specific anti-COVID-19 drug. Subsequently, Paxlovid imported the first batch of 2 1.2 million boxes, and sent them to Jilin, Guangdong, Fujian, Guangxi, Shanghai, Zhejiang and other provinces after customs clearance.
Pfizer official website showed that the product specification of nemativir tablets was 150mg/ tablet, and that of ritonavir tablets was 100mg/ tablet. The recommended dose is 300mg of nematevir combined with 100mg of ritonavir once every 1 hour for 5 days.
Professor Jin Dongyan, a virologist at the School of Biomedicine, Li Ka-shing Medical College, the University of Hong Kong, once told the media that patients with paciclovir had the best effect within 72 hours after infection, and the drug was of little value in severe cases. Moreover, the data show that the drug is more effective for the elderly over 65 years old and people with basic diseases, reducing the mortality rate by 865,438+0%, but has no obvious benefit for other age groups of 40-64 years old.
At the press conference held by the State Council Joint Prevention and Control Mechanism on February 20th, 65438, Wang Guiqiang, director of the Department of Infectious Diseases of the First Hospital of Peking University, said that the diagnosis and treatment plan recommended three anti-COVID-19 drugs, including monoclonal antibody, the combined packaging of nimativir tablets and ritonavir tablets, and afudin. Early use can reduce the occurrence of serious diseases, shorten the course of disease and the time of virus detoxification.
Wang Guiqiang said that it is a small molecule antiviral drug with mild indications and is an ordinary patient. When using, we should pay special attention to the interaction between drugs; If the elderly with basic diseases are taking drugs such as simvastatin and amiodarone, they can't use them.
At that time, Wang Guiqiang also stressed that these three anti-COVID-19 drugs should be used under the guidance of medical institutions and doctors. "Antiviral drugs will be gradually provided at the level of medical institutions and communities, and infected people, especially severe and high-risk groups, will be used reasonably under the guidance of doctors."
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