What will happen to humans after they immigrate to Mars?

Hello, the climate of Mars is not as hot as Mercury and Venus, not as cold as Pluto, and not as uninhabitable as gas giants such as Jupiter and Saturn.

However, the surface temperature of Mars is more than 30℃ lower than that of Earth, and the temperature difference between day and night often exceeds 100℃. The main component of the earth's atmosphere is nitrogen (78%), but the main component of the Martian atmosphere is carbon dioxide (95%) (the content of carbon dioxide on the earth is 0.04%), which is thinner than that on the earth. Therefore, if human beings want to immigrate to Mars, they must first overcome a series of harsh environmental factors.

The gravity of Mars is lighter than that of the Earth, so the human bone density may be rapidly lost. Centuries later, the human bones on Mars may become thicker. Generally speaking, it will look bigger than the earth. In addition, the radiation problem on Mars, in order to combat radiation, the human body may secrete more carotenoids, resulting in the whole body showing orange.