Conditions of mobile phase of benzophenone hydrazone

Chemical substance

China? |? This entry is reviewed by the writing and application project of "Popular Science China".

Benzophenone hydrazone is a chemical substance. CAS number: 5350-57-2. Molecular weight: 196.25. Psa: 383,800 pounds. LogP:3.09800. White crystalline powder.

Chinese name

Benzophenone hydrazone [3]

Foreign name

Benzophenone hydrazone [3]

chemical formula

C 13H 12N2[3]

molecular weight

196.25

Chemical abstracts service registration number

5350-57-2[3]

Physical and chemical properties of basic information, production methods and uses of safety information, calculation of molecular structure data, chemical data, first aid measures, fire prevention measures, leakage, emergency treatment, operation, disposal and storage, ta said.

Basic information

Chinese name: benzophenone hydrazone

Chinese alias: diphenyl diazomethane precursor; Benzophenone hydrazone; benzophenone hydrazone

English name: Benzophenone Hydrazone

Si Nuo. : 5350-57-2

Molecular weight: 196.25

PSA:38.38000

LogP:3.09800[ 1]

physicochemical property

Appearance and properties: white crystalline powder

Melting point: 95-98 degrees Celsius (liter. )

Boiling point: 225-230℃ 55 mm Hg (liter. )

Flash point: 146℃

Refractive index: 1.677

Storage condition: 0-6? C

Safety/security information

Packaging grade: Grade III

Hazard category: 6. 1

Customs code: 29280090

Dangerous goods transport code: UN28 1 1

Germany WGK:3

Hazard category code: R22

Safety instructions: S22-S24/25

RTECS number: PC4954487

Dangerous goods sign: Xn

Production methods and uses

The anhydrous ethanol solution of benzophenone and anhydrous hydrazine were refluxed for 65438±00h hours, and benzophenone hydrazone was precipitated after cooling, with a yield of 87%.

Used as organic pigments and pharmaceutical intermediates.

Molecular structure data

1, molar refractive index: 62.32[3]

2. Molar volume (cm3/mol): 186.3 [3]

3. Isotonic specific volume (90.2 k): 473.6 [3]

4. Surface tension (dyne/cm): 4 1.7 [3]

Computational chemical data

1. Reference value for calculation of hydrophobic parameters (XlogP): None.

2. Number of hydrogen bond donors: 1[3]

3. Number of hydrogen bond acceptors: 2[3]

4. Number of rotatable chemical bonds: 2[3]

5. Number of tautomers: None

6. Polar surface area of topological molecules: 38.4[3]

7. Number of heavy atoms: 15[3]

8. Surface charge: 0[3]

9. Complexity: 19 1[3]

10. Isotope number: 0[3]

1 1. Determine the number of atomic solid centers: 0[3]

12. The number of uncertain atomic solid centers: 0[3]

13. Determine the number of solid centers of chemical bonds: 0[3]

14. The number of solid centers of chemical bonds is uncertain: 0[3]

15.*** Number of valence bond units: 1[3]

Emergency treatment

Emergency rescue:

Inhalation: If inhaled, please move the patient to fresh air.

Skin contact: take off contaminated clothes and rinse skin thoroughly with soapy water and clean water. If you don't feel well, see a doctor.

Eye contact: separate eyelids and rinse with running water or normal saline. See a doctor at once.

Intake: gargle without vomiting. See a doctor at once.

Suggestions for protecting rescue workers:

Move the patient to a safe place. Consult a doctor. Show this chemical safety technical specification to the doctor at the scene.

fire fighting

Fire extinguishing agent:

Use water mist, dry powder, foam or carbon dioxide fire extinguishing agent to extinguish the fire.

Avoid using direct current water to put out the fire, which may cause flammable liquid to splash and spread the fire.

Fire precautions and protective measures:

Firefighters must wear air respirator and full-body fire suit to put out the fire in the upwind direction.

Move the container from the fire to an empty place as much as possible.

If the container in the fire changes color or the safety pressure relief device sounds, it must be evacuated immediately.

Isolate the scene of the accident and prohibit irrelevant personnel from entering. Contain and treat fire water to prevent environmental pollution.

Emergency treatment of leakage

Protective measures, protective equipment and emergency procedures for operators:

Emergency personnel are advised to wear air respirator, antistatic clothing and rubber oil-resistant gloves.

Do not touch or cross the leak.

All equipment used during operation shall be grounded.

Cut off the leakage source as much as possible.

Eliminate all ignition sources.

According to the influence area of liquid flow, steam or dust diffusion, the warning zone is defined, and irrelevant personnel are evacuated to safety from crosswind and upwind.

Environmental protection measures:

Contain the leakage to avoid polluting the environment. Prevent leakage from entering sewers, surface water and groundwater.

Containment and removal methods of leaked chemicals and disposal materials used: a small amount of leakage: collect leaked liquid in a closed container as much as possible. Absorb with sand, activated carbon or other inert materials and move to a safe place. Don't rush into the sewer. A large number of leaks: damming or digging holes to contain them. Close the drainage pipe. Cover with foam to suppress evaporation. Use explosion-proof pump to transfer it to tank car or special collector, and recycle it or transport it to waste disposal site for treatment.

Operation, disposal and storage

Precautions for operation:

Operators should be specially trained and strictly abide by the operating procedures.

Operation and disposal should be carried out in places with local ventilation or comprehensive ventilation and ventilation facilities.

Avoid contact between eyes and skin, and avoid inhaling steam.

Stay away from kindling and heat sources, and smoking is strictly prohibited in the workplace.

Use explosion-proof ventilation system and equipment.

If canning is needed, the flow rate should be controlled and grounding devices should be provided to prevent static electricity accumulation.

Avoid contact with prohibited compounds, such as oxidants.

When handling, handle with care to prevent the packaging and containers from being damaged.

Empty containers may leave harmful substances behind.

Wash your hands after use, and don't eat or drink in the workplace.

Equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment.

Precautions for storage:

Store in a cool and ventilated warehouse.

Should be stored separately from oxidants and edible chemicals, and should not be mixed.

Keep the container sealed.

Stay away from fire and heat sources.

The warehouse must be equipped with lightning protection equipment.

The exhaust system should be equipped with grounding device to guide static electricity.

Adopt explosion-proof lighting and ventilation settings.

It is forbidden to use equipment and tools that are easy to generate sparks.

The storage area should be equipped with emergency response equipment for leakage and suitable accommodation materials. [2]

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reference data

[ 1]? Xu kexun Introduction of organic chemical raw materials and intermediates: Liaoning Petrochemical Technology Information Center, 1997.

[2]? Chemical Registration Center of State Administration of Work Safety. Encyclopedia of Safety Technology of Hazardous Chemicals (3rd Edition): Chemical Industry Press, 20 17.

[3]? Benzophenone hydrazone Chemical source network? [reference date 2022-09-06]

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