How did uncle die in the second season of Armored Punch?

This disease needs drug support, and syncope will occur.

This is uncle's process:

What caused Joe to become so decadent and needed medicine to continue his life? These two episodes still have no explanation. Joe seen in these two episodes is a cripple, sloppy and thin, and there is no blood on and off the stage. Fortunately, he once had a large number of fans, many of whom were grown up by children of that year.

It happened that he met someone who could pull him out of the mire. This man is the uncle who played fake games with him. My uncle's son is a fan of Joe, so my uncle also knows his past. Seeing that Joe is now a loser, I want to give him a hand. Joe began to reflect on himself in several serious conversations with his uncle and wanted to "live for his dreams again".