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Int is in progress. Radiation oncology biology. Physical education class, Book One. 58,65,438+0,246,5438+0-246, 2004
Copyright. Elsevier company in 2004
American printing. property in copyright
0360-3016/04/USD-see the previous article.
Tujing:10.1016/s0360-3016 (03) 01431-7.
Clinical study of breast cancer
Randomized, paired comparisons will not sting the barrier film.
Silver sorbose cream for skin care (10% glycerol)
Postoperative irradiation
Peter Graham, franzcr, * Letter of Intent Brown, Ph.D. student * Anne's CAPP, franzcr,
Christopher fox. * Julie Hollis, dip.app.sc, and
Ilias Nasser
Kogarah Cancer Care Center, St George's Hospital, University of New South Wales, Australia; . Cancer nursing
Wollongong Hospital Center, University of New South Wales, Australia
Objective: Postoperative irradiation provides a good model for skin care, because
Compared with the relatively unified surface water and radiation, under what circumstances will radiation induce humidity?
Desquamation is common. We designed a study to test the effectiveness of the preventive 3-meter cavilon barrier.
The film (no thorn) compared with the wet desquamation rate, sorbitol cream (10% glycerol).
Materials and Methods: The irradiated chest wall was divided into medial and lateral parts. 6 1 female
Randomly, there is no acupuncture application, whether it is the medial or lateral half, the alternate half is treated.
Sorbitol.
Results: the skin toxicity of all patients, the area under the calculated curve, is equal to no stimulation and sorbitol.
The scores were 8. 1 to 9.2(p respectively (P
0.005, wilcoxon signed rank sum test). Total humidity cycle
The desquamation rate is 6 1 case is 40 to 45, which is equivalent to an average of 0.65 weeks and 0.74 weeks for each patient.
The areas without sting and sorbitol treatment are respectively. The wet chip removal rates were 33% and 46%, respectively (P.
0.096, accurately test McNaima). 58-year-old fully taxed patient (observed for at least 7 weeks), region
According to the curve and the wet desquamation of interest rate, there is statistically significant difference (P.
0.002 and 0.049,
Respectively). There was no significant difference in pain score. The score of itching is as follows
Significantly reduced, in the non-thorn area (lower area curve, P.
0.0 1 1 ) 。
Conclusion: The duration and frequency of NO-Stine reduction is the moisture desquamation caused by radiation.
. Elsevier company in 2004
Radiation, toxicity, skin barrier.
Introducing a barrier-free movie may delay normal body peeling.
Conversion rate, reduce the impact of wear and tear. Some skin
Skin reaction is a common adverse result, which is used by radio protectors to reduce the damage of adhesive to skin.
Treatment (RT). The skin surface is opposite to the magnetic tape after operation. Non-thorn is an excellent product, which consists of at least two factors.
Good test bed for uniforms and skin care protocols. Compared with the other five similar products, we regard this as.
It is assumed that skin abrasion contributes to the overall re-measurement of skin hydration after repeated adhesion.
Action. Therefore, the service life of the whole tape application and peeling is prolonged (1). We chose this product.
Keratinized surfaces may increase the chances of skin care that basically meets our standards.
The stem cell pool will be fully regenerated to reduce sorbitol, which is a universal label for giving skin barrier cream.
Possibility of wet desquamation. Another possibility is to sell mixed water and oil made in Australia.
Keeping the surface intact will help to keep glycerol, which usually contains 10%.
Humidity level and support are for relocation/maintenance.
The most efficient maintenance process. In other words,
Materials and methods
Modify the physical environment, skin, not
Radiation damage than radiation may be modified based on previous records of skin reactions in our.
Radiation damage of phenotypic expression. Prospective RT toxicity database, baseline
Reprinting requirements: Peter Graham, franzcr, cancer identification support in the form of cavilon for 3 months.
Nursing center, St. George's hospital, ashes, Cogala, New South Wales, 2265438+2007 Non-piercing barrier membrane was conducted for free research.
Australia. Tel: 61-2-9350-3934; Fax: 61-2-9350-3958; E-mail: February 2003 1 1 received, revised on June 3, 2003.
Grahamp@sesahs.nsw.gov.au was accepted for publication on June 23rd, 2003.
Cognition-this is a study initiated by investigators; 3 meters is
24 1
International radiation oncology ●
Biology ●
physics
Figure. 1 。 Schematic test layout.
The wet desquamation rate was RT after operation.
St George's Cancer Care Center undertakes 60%. that
The sample size is selected to provide 80% power detection.
Reduce the humidity desquamation rate to 30%. south
Health service ethics in eastern Sydney and Irawala
The Committee approved the study and all the participants provided it.
Written informed consent. 6 1 patient
Recruit St. George of RT department (.
50) and
Wollongong (.
1 1) hospital.
Postoperative chest wall is divided into medial chest wall and lateral chest wall.
The lateral spacing is about in the middle of the clavicle.
Line (figure 1). The randomness of these areas is either
Thornless movies or sorbolene applications. internal control
Methods account for differences between patients, such as using
Chemotherapy and internal randomization are for protection.
Potential skin reaction system.
To make matters worse, whether indoors or outdoors. at will
Connect to a separate data management unit by telephone.
If the film is assigned to it, it will be applied twice a week.
If assigned to the outside, 3 times a week.
Between. This is because the pilot experience shows that
With the accumulation of products, the application of products is more frequent.
Between the inside. Application of non-barbed film
The nursing staff is responsible for ensuring compliance and correction by both parties.
Even if a colorless movie is shown. Application of sorbosone
Twice a day. RT days, nurses are also suitable for sorbolene.
Once a day, apply sorbolene to patients at other times.
This product is suitable for using RT from the beginning to 2 weeks.
When it's done. For the field of skin, developed countries are wet.
Dandruff removal, skin care in this respect, changed to 1.
Hydrophilic colloid dressing.
Reverse transcription of chest wall management using 6 MV photons.
The beam is suitable for cutting. Clear the chest wall
25 ingredients, the dosage is 50 Gy. All patients were 65438±0cm.
Pills are suitable for daily use. Is this for the whole chest wall?
( 。
17), or 4 cm wide, with 8 cm on both sides.
Width) the total length of the scar (.
44) at
The cancer of caution. For 6 1 case, 49 cases were received.
Clavicular field and 17 axillary field. 6 cases
Vol. 58,No. 1, 2004
The electron enhancement of 10 Gy acts on five components.
Recurrent chest wall resection. Only these patients
Qualified, if the division of the electron field is evenly divided by the invertebrate.
And sorbitan surface.
Dermatologists made a speech on evaluation score: every week.
Acute skin radiotherapy in tumor group
Scores. The patient completed the Likert scale of 5 points (the lowest
The value is 1, and the maximum value is 5) The weekly pain and itching are
All areas of the skin. Polaroid's photo was taken to.
Every week. The evaluation lasts from 1 week to completion.
Skin reaction or symptom solution, or at most.
12 evaluation. If the skin reaction has been resolved
Pre-completion 12 weeks, and subsequent evaluation.
Week 12 was given zero.
Thus, the dichotomy (threshold) of both sides is analyzed.
The area under the curve. Threshold comparison
This test uses mcnemar's exact test pairing.
Confidential data. The area values under the curve are obtained respectively.
By summarizing the values of weekly scores. weekly
Considered as a unit of time. radiotherapy
The skin score of the tumor group provides the value of this area.
(radiotherapy tumor group scored high.
1
A week) as a unit of time. If the reaction
The score is 0,0,0, 1, 1, 2,2, 1, 0,0 is the week 1, 12,
Add these together to get a value of 8 (under the total area
Curve provided by histogram, weekly score).
Compared with these people, the rank sum test with Wilcoxon symbol is used.
A complete set of three thermoluminescence dosimeters is provided for 14 patients.
And cinematography (Wayne Chemical Company, New Jersey)
Dose measurements were obtained at 12 locations nationwide.
One component of the chest wall is parallel to the dosimeter along the central axis.
Comparative study. For those patients, who
Use pills, because after that, the scar will extend upward,
The pill is removed from the central shaft. This report is
Don't care about dosimeter performance, but abstract.
The result of thermoluminescence dosimeter is
Brief expression of the relative amount of national public welfare fund
The central axis of the wall. Uniformly and randomly distributed, so that
2 skin care products, both internal and external.
Prevent system, dosage, etc. from changing.
Friction field and other factors lead to skin changes.
Reaction.
result
The average age of patients is 58 years old (ranging from 30 to 88 years old). that
Left side treatment, 27 cases. 4 1
The patient is menopausal. 8 people, Asia, 1
Black, the rest is white. 37 patients
Chemotherapy, at least in
13 part of the order completed at the same time is 24.
19 patients received anthracycline chemotherapy, but
I didn't receive this. I also used rt. Average dose RT
It's 49.7 Gy (range 38 -60). Only 2 cases were not completed.
Reverse transcription is proceeding as planned. These two stopped because it was early.
Skin reaction. All white, copy that. Parallel.
Chemotherapy. Four patients interrupted radiotherapy. ...
Radiotherapy skin care ●
Sports Graham and others.
Table 1. Analyze the recruitment of all patients (.
6 1) analysis, for skin reaction and itching, score less.
Result area curve p
In the no-stab area. Statistics without evidence.
Significant trends between pain scores or
Requirements of rtog skin score for analgesia. Nine patients need painkillers.
There were 8 cases of 9.2 0.005 * skin reaction of sorbitol in the area of sorbitol.
Spineless 8. 1 spineless area.
painful
Sobolene10.90.17 * The average dose value shown in Figure 2 is nationwide.
No thorn 10.6 chest wall, if all places are fully photographed (standard
Itching deviation [Statistics Department] 0. 196). Figure 3 shows the overall meaning.
The percentage of the value of sorbolene12.9 0.011* dosimeter, including the proximate cause of position.
No thorn 1 1.9, with bundle edge or not pressed (standard deviation 0.34). very clear
%, there are no different systems of chest wall in China.
Skin grade 2 score, except pill status. Although the dose is correct
Sorbene 46 0.096. The central axis seems to be lower than the overall transverse direction, but the pill does not.
The invertebrate portion 33 extends from the inside to the outer boundary, but this is not always the case.
Pain score 1
0.42 。 On the central axis of the dosimeter belt.
Sorbene 43
The location of the thorn 36. The region made 64 suggestions.
Scratch scores two. No pills. Average dose per time, in sorbo-
Sorbene 39 0.0 19 .Lene skin irradiation therapy10.46 (standard deviation 0.2 19), and with nano.
2 1 skin irradiation for stinging therapy 1.50 (standard deviation 0.257), not clinical or
Statistically significant difference (P.
0.55, t test). that
* wilcoxon signed rank sum test.
. That's right. Mcneima test. Curve value under wet area and interest rate.
Overview of desquamation formula and skin care products
In Table 3. There is no difference, there are statistics, sigtwo,
This is mainly due to the obvious skin reaction, although the trend seems to be larger skin.
Non-thorn area The reaction is in the horizontal direction and thus distorted.
3 1 patient were randomly divided into two groups: needless acupuncture group and 30 transverse application group.
Specific application
The invertebrate group.
No thorns. Therefore, the analysis will be completed as planned.
Point use, all patients (intention to deal with analysis)
discuss
See table 1 for the summary. The analysis of preventive measures for complete taxation is often used for the purpose of re-taxation.
Patients, but not those who have no available information after inducing radiation-induced skin reactions, although there are several con6.
Weeks, summarized in table 2. Anyway, trolled's experiment has been completed. Preventive topic ascorbic acid
Acid and placebo were tested, and 85 cases underwent skull surgery.
There was no significant difference in RT, and (2) was found. aloe oil
Table 2. Analyze the patient's total tax payment (.
58) has not been proved to be superior to placebo in randomization.
Results The area curve P was a double-blind comparison, whether it was placebo gel or untreated.
( 3 ) 。 The topic of hyaluronic acid in mixed population is
The Rtog skin score was displayed in a randomized double-blind trial to reduce the peak period.
Sorbene 9.6
No stinging 8.4
0.002 * Radiation skin reaction and overall curative effect (4). maybe
Pain is limited by hyaluronic acid research, including small-scale research.
Sobolene11.30.11* weapons distribution and
There is no sting 10.9 lack of regression analysis to exclude other skin reactions.
Itching indicates influential research results. not have
Sorbene 13.2
No thorn 12.3
0.0 17 * In addition, hyaluronic acid has several characteristics.
% can contribute to the results of positive clinical trials.
Hyaluronic acid binding fibrin provides a mechanism.
Skin score 2
Sorbene 48
No thorn 33
Pain score 1
Sorbene 43
0.049 。
0.27 。
The support of ICal is beneficial to the migration of related cells.
Repair. Hyaluronic acid stimulates the migration of phagocytes,
Fibroblasts and endothelial cells proliferate (5 -8). obviously
The important physical and chemical properties are its ability.
No thorn 34
Itching score 2
Sorbene 40
No thorn 2 1
0.0 12 。
Eagerly retain moisture (9).
The main assumption is possible benefits.
On the surface, it reduces the exposure of stinging to the skin.
Loss of skin layer due to normal wear and tear. lip-deep
* wilcoxon signed rank sum test.
. That's right. Mcneima test.
Pattern (not statistically significant) response is a kind of.
Small mistake, it's horizontal twist.
International radiation oncology ●
Biology ●
Vol. 58,No. 1 2004
Figure. 2 。 Average thermoluminescence dosimeter dose per measurement transverse to the inner side of the central axis (position 1)
(Location: 12) Take full pills every time.
If there is no thorn, it conforms to the hypothesis, and if there is no thorn, it is.
Effective mechanism to reduce apparent wear.
Because of friction, because it is considered to be greater, in
Transverse spacing. Although we didn't test the machine
Support model for enhancing cell migration
Cells, if the skin surface remains unchanged, this is reasonable.
Predict more effective repairs. In addition, although
Its purpose is not to combine water, it has.
It is shown that transdermal water movement is reduced. no matter
The basic mechanism of this study provides
There is strong evidence to show whether the non-woven membrane reduces the phenotype.
The performance of radiation injury, even without radiation.
Protection is currently at the molecular or cellular level.
There is no evidence that there is any indication that sorbolene should
More or less often used to reduce skin reactions.
This research is still standard practice.
Use sorbolene in our organization. Movies, at
It's the last few days of design. More frequent
The application of movies will lead to accumulation and
It often causes movies, blows and peels, thus reducing its.
Potential benefits. Regardless of application
The frequency is most suitable for these two products. In this study,
Using the specified application, the skin reacts less.
The fields involved in the film. This research continues to be used.
Standard products are controlled and managed in a standard way.
Test this is a new product, what to consider.
Figure. 3 。 Average thermoluminescence dosimeter dose per measurement transverse to the inner side of the central axis (position 1)
(Location 12) All measures, regardless of pills.
Radiotherapy skin care ●
Sports Graham and others.
Table 3. Skin reaction patterns between skin.
AUC n of atrioventricular product
damp
desquamation
( % )
shelving
inside
Sorbene
Thornless
Sorbene
Thornless
3 1
30
30
3 1
9.85
7.73
8.73
8.52
58
33
33
32
Abbreviation: United Self-Defense Forces.
Area under curve (fraction).
This method is most likely to benefit from the product. it
It can be a different application frequency.
Leading to different results; However, this has not changed.
Explain the current research or declare the results invalid.
This survey shows that movies are better than sorbolene.
Suitable for research in this field, but it is possible, whether it is
It's better than no preventive skin care. We don't know anything
Compare the treatments that sorbolene didn't have. However, due to
Sorbolene is the existing treatment standard in our department.
Skin care without it is ethically difficult.
Arm. Untreated areas are also more difficult.
There are patients who agree to participate, especially when they are patients.
Information pamphlets and manuals are provided to our patients,
Developed countries in China and various countries with cancer.
Information organization, describes the skin care cream.
So, although scientific, it may be pure.
There is no treatment area, which is not a feasible design for us.
Department. However, regardless of the value, each
Without treatment, this is still an effective comparative study.
These two products.
The amount of sorbitol is not enough to provide
The effect of a pill has not accumulated to any significant degree.
Thickness of filler. Skin dose data, not.
There was no significant difference in pill area. At present, there is no significant difference.
Structural effect (or lack of structural effect) between sorbitol and NO-
Stine covers the skin outside these areas with pills.
Materials. There is no difference in dose in the following areas.
Umaru explained the results of this study.
The study plan did not prospectively define the minimum quantity.
After several evaluations, one of the patients did not.
Taxable is a skin reaction. Obviously, from the data,
However, busy skin reactions can last for weeks.
RT after completion (Figure 4). Including patient analysis.
People who haven't been evaluated for more than six weeks, so,
Also underestimated the occurrence of skin reactions.
Underestimating the potential impact is not an obstacle.
Movies. Therefore, we recommend that all patients be analyzed (intention
Processing analysis), regardless of quantitative evaluation,
58 cases had rejection.
3 cases were only evaluated for 2-6 weeks. that
The main reasons for these patients losing data are
The failed therapist recorded the skin assessment.
Once this is a test and monitoring test, there is no need for additional.
The patients being treated are recruited by doctors.
Research to avoid the problem of missing data erosion.
Test the learning ability of hypothetical design.
Figure. 4 。 Average weekly physician skin score.
Lowering the itch score is the opposite.
Because there is a dry feeling on the skin of a movie without thorns,
Moisturizers, no stinging, lack of universal use in movies.
Treat skin itching, which is the predictive score of itching.
It may increase in the field of non-stinging treatment. lack
Effects on pain may include changes in feelings in the following areas
Postoperative flap.
Choose wet desquamation as incision.
Dichotomy analysis of skin reaction, because of its clinical
Relevance and importance. Is there any previous data?
The patient has itching or pain in this aspect. Cutting point
These results selected patients to be similar.
Large groups and small groups are analyzed. Area analysis under curve
When choosing the entry point, it is not affected by potential prejudice.
Analysis, and highly consistent, with dichotomy.
Analysis. The reason is that the peeling rate of low humidity is in
We compared the treatment field of sorbosone with the historical control.
May involve reducing the use of fillers, because
Who is the clinician who treats most patients and who provides these patients?
Keywords historical data design, research and utilization, whole chest wall pill,
But his patients accounted for 10% of these recruits. This study
It is not used to evaluate the clinical application value of fillers.
How much is this clinical background used? Use pills
Australia is full of variables, although most departments and
Clinical filler (10). Although this may affect the size.
This study is helpful to understand the clinical situation.
The intention is that the potential benefits of this model may become
Is suitable for any wet desquamation of skin area with obvious danger,
Such as head and neck radiotherapy or groin radiotherapy.
Area.
Introduce the bisector and lower area on both sides.
The reasons for choosing curve analysis are as follows. frequency
A threshold, the skin response score is easy to understand.
And more easily understood dimensional terms.
Effect. However, beyond a certain threshold, the change may be masked.
The size of the area, the projects and time involved, and the solution.
This reaction. The area analysis under the curve not only reflects
The degree and duration of the reaction,
Generally refers to reflect the overall damage of enterprise groups, aluminum
246-j Radiation Oncology ●
Biology ●
Vol. 58,No. 1 2004
Table 4. Cost-effective sorbitol and skin care with non-woven film
patient
skin care
expense
(Australian dollar)
Zhou dressing
(noun)
Dressing cost *
(Australian dollar)
Per capita cost
Patient * (AUD)
Sorbene 75074 13779 USD (8599-22585) 147 (95-235)
100 no sting 23716512103 USD (7553-19838)145 (99-222).
Abbreviation: Australian dollar.
Australian dollar.
* All nursing management in outpatient department; The scope (in brackets) includes home visits by community nurses, and there is no nursing input.
Although doctors may not have the same intuitive appreciation.
Final score. The purpose of this study is to use
Wet desquamation threshold because there is no previous data.
It can be used for area analysis under curves. explain
If differences are found, the influence of clinical nursing should be carried out immediately.
That's right, it is inferred that 100 cases, 9 weeks of dressing.
The required moisture shedding can be avoided.
There is no prospective record of individual patient cost data;
However, the relative cost can be estimated (Table 4).
According to our current wet desquamation treatment practice,
The strategic cost of thorn-free is 1%, which is lower than sorbolene strategy.
The average cost per patient was 145 USD and 147 USD.
Nursing management is our clinic. according to
The number of nursing resources allowed (including from
It is unlikely that the value will be zero, to 20 minutes, in the clinic, community.
Nursing visits, on the home page), using no thorns, will range.
From 4% to 6%, in overall skin care.
Cost. Our consistent policy is to arrange community nurses.
Once modified during reverse transcription, there is no
Testing in our system will save costs. expense
Films that are not effective may be adapted to local conditions.
Management practice and health care of wet desquamation
System. In addition to monetary considerations, this will also
A lot of nursing time (20 outpatients to 45 hours of community nursing)
Every 100 cases) is convenient for patients. all
It is impossible to compare the quality of life with this study.
Design, because every patient is under his own control; however
We have reported special treatments for these symptoms.
Skin report, the most common patient.
Make full use of this special research design
Compared with the past, random skin care attempts
Irradiated skin responds to the use of internal controls.
Exclude results that affect other variables.
Furthermore, after a very uniform test bench operation,
Patients use it to replace skin.
Different websites, such as head and neck or groin or patients.
Very changeable radiation technology, dose and segmentation.
The survey results from these two aspects are relatively strong.
Unfortunately, due to the very different appearance and
The frequency of application between these two products is different.
A study of possible blindness. Due to the above limitations,
Although we would recommend spineless as effective.
The form of RT in skin care will be studied many times.
Large-scale multi-span Tasman radiation oncology department
Trial version and several enhanced versions. Kawenlong has no backbone and is durable.
Barrier films are now available in the form of frost,
This applies to more frequent. This is good for a person.
A double-blind design was used to compare cbdc and sorbitol.
300 patients will be recruited for digital imaging.
If you need a greedy score.
involve
1 。 Grove chlorine, Leiden JJ, Lutz jb, etc. Compare skin.
Protective agent performance of various films and molded products. data
It has been three months since this document was published.
2 。 ? Church of Berlin, Gaspar Sheng, George S,
Waiting for someone. Double blind
A randomized prospective trial to evaluate local vitamin C.
The solution is to prevent radiation dermatitis. Explain j-rays
Tumor Biology physical education class1993; 26:4 13-4 16 。
3 。 Ms. Williams, Berkemi, chlorpromazine, etc. Third-stage double
Blind evaluation of aloe gel as preventive agent
Skin toxicity caused by radiation. Physical education class's Interpretation of Radiation Tumor Biology
1996 36 (supplement 1) :345-349.
4 。 Guo, Gu C, Paisgreen, et al. Double blind, random
Clinical study comparison, hyaluronic acid placebo
The patient is receiving radiotherapy. Radiation Oncology1997;
42: 155- 16 1 。
5 。 Ying, Fapris, bharathi, etc.
Effects of experimental skin injury: macro and micro
And the healing was observed by scanning electron microscope.
Process. Interpretation of J-tissue reaction,1986; 8:533-544 。
6 。 Van Derrini IV Osservazioni clinic
Ialuronicao is in terapia Dermatology Department. Gram-Swedish Chinese dermatosis
1985; 120:5- 10 。
7 。 Dr weigel, more comprehensive General Motors, leboeuf Road. The role of the model
Hyaluronic acid and fibrin are active in the early stage.
Inflammatory reaction and wound healing. J theoretical biology1986;
1 19:2 19-234 。
8 。 West DC, Hampson Lane, Arnold Architecture and others. Induction of angiogenesis
Hyaluronic acid in degradation products. 1985 science; 228 :
1324 rpm 1326.
9 。 Nakamura Kuniwo rice, Xitian spoon, recent development, in use.
Hyaluronic acid is healing the wound Experimental drug opin investment1995; 4 :
175- 188 。
10 。 Delainik, blakey Development, drummond Studies and others represent this.
Medical college radiation oncology, radiation oncology consultation
Status of the National Breast Cancer Center Group. Radiotherapy for breast cancer;
The statistical investigation results of 1 ANZ show that the current processing technology.
200 1 year radiotherapy in Australia; 45: 170- 178 。
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