There are several affiliated hospitals in South China University.

University of South China has six affiliated hospitals, namely the First Affiliated Hospital, the Second Affiliated Hospital, the Third Affiliated Hospital, Changsha Central Hospital and Public Health Hospital. The First Affiliated Hospital of South China University is located at No.69 Chuanshan Road, Hengyang City, Hunan Province, covering an area of 124.99 mu, and was founded in 1943. It is a three-level general hospital integrating medical treatment, teaching, scientific research, prevention and rehabilitation.

The Second Affiliated Hospital of South China University is located at No.35 Jiefang Avenue, zhengxiang district, Hengyang City, Hunan Province, with a total area of 150 mu. Established in 1949, it is a tertiary general hospital. The hospital has departments such as urology, neurology, intensive medicine, gastroenterology, endocrinology, respiratory medicine, cardiovascular medicine, hematology, oncology, radiotherapy, nephrology rheumatism, hepatobiliary, splenic and pancreatic surgery, obstetrics and gynecology, pediatrics and so on.

The cooperative affiliated hospitals of South China University are:

Hengyang Hospital affiliated to University of South China (Hengyang Central Hospital), Xiangtan Hospital affiliated to University of South China (formerly Xiangtan First People's Hospital), Loudi Hospital affiliated to University of South China (formerly Loudi Central Hospital), Shaoyang Hospital affiliated to University of South China (formerly Shaoyang Central Hospital), Huaihua Hospital affiliated to University of South China (formerly Huaihua First People's Hospital);

Yongzhou Hospital affiliated to University of South China (formerly Yongzhou People's Hospital), Chenzhou Hospital affiliated to University of South China (formerly Chenzhou First People's Hospital), Guangdong Second People's Hospital affiliated to University of South China (formerlyNo. 177 Central Hospital of the People's Liberation Army) and Liuyang Hospital affiliated to University of South China (formerly Liuyang People's Hospital).