What is the national standard test method of calcium hydrogen phosphate?

Calcium hydrogen phosphate is a white monoclinic powder, odorless and tasteless. Usually dihydrate, chemical formula is cahpo4.2h2o, which is stable in air. When heated to 75℃, the lost crystallization water becomes anhydrous, and when heated, it becomes pyrophosphate. Soluble in dilute hydrochloric acid, dilute nitric acid and acetic acid, slightly soluble in water, insoluble in ethanol. External stability method is mainly used in domestic production. Put disodium hydrogen phosphate and calcium chloride solution into the reaction kettle at the same time, and stir to make them fully mixed. Adding calcium chloride solution, adding stabilizer magnesium emulsion and sodium pyrophosphate solution, stirring evenly, then standing for 0.5h, then filtering, washing with water, drying and grinding the precipitate.

The international inspection method of calcium hydrogen phosphate aims to achieve the consistency of safety and effectiveness with reality, that is, the curative effect is equivalent to reality and the safety is not lower than that of listed products. Different production units may have different bases to achieve this goal, that is, different API production processes and preparation processes may be adopted, which may lead to different product quality control methods. Therefore, in its research, the existing national standards cannot be mechanically applied, and the principle of imitating varieties rather than imitating standards should be followed, that is, in the testing process, personalized registration standards should be formulated for specific varieties with the goal of consistency of safety and effectiveness. Its international inspection method is GB 22549-2008-T.