Does the nucleic acid test negative still need isolation? Can I go to work if the nucleic acid test is negative?

As we all know, nucleic acid detection is a common diagnostic project, which can diagnose novel coronavirus in a short time, which is of great help to the prevention and control of novel coronavirus. Many people will have nucleic acid tests, especially those who return to work. So is it necessary to isolate the negative nucleic acid test? Let's take a closer look!

Does the nucleic acid test negative still need isolation? It depends. If it is an ordinary person, the general nucleic acid test is negative, and the isolation period is 14 days, there is no need for isolation. If it is a close contact or a suspected patient, negative nucleic acid test does not rule out the possibility of false negative, isolation can not be completely lifted, and multiple tests are needed to confirm the diagnosis.

After contact with suspected or confirmed cases, it is necessary to conduct isolated observation. If there is no disease, then nucleic acid detection is the standard of whether isolation can be lifted. If the patients infected with COVID-19 virus are negative in nucleic acid test for two consecutive times (at least every 1 day) after treatment, there is no need for hospital isolation. But I have to stay at home and observe for a while. There have been many reports that after the patient recovered from hospital, the nucleic acid test was positive again. In addition to sampling errors and other reasons, considering that there is still a small amount of virus residue in the patient's body, for the sake of safety, it is necessary to conduct self-isolation at home for a period of time after discharge. And the patient's nucleic acid test is negative, even if he doesn't carry novel coronavirus, it doesn't mean he has enough anti-novel coronavirus antibodies. When you come into contact with novel coronavirus again, you will also be at risk of being infected.

Can I go to work if the nucleic acid test is negative? Ordinary people can go to work normally after the quarantine period is over. If it is a close contact or a suspected patient, the nucleic acid test is negative, and it needs to be isolated for observation and cannot go to work.

Novel coronavirus test was negative, that is, novel coronavirus nucleic acid test was negative in nasopharyngeal swab, sputum, lower respiratory secretions, blood and other samples. When the test is negative, its clinical significance should be analyzed in detail. When the virus nucleic acid test of the patient to be diagnosed is negative, it may be uninfected or infected but not detected. At this time, false negative results will appear. False negative may be related to the severity of the disease, the development stage of the disease, unreasonable sampling specimens and testing equipment. Therefore, false negatives should be comprehensively analyzed according to their clinical manifestations, epidemiological history and chest CT changes, and viral nucleic acid detection should be carried out many times when necessary. If the virus nucleic acid test is negative after treatment, the disease has been cured. Therefore, sometimes we can't rule out infection just because novel coronavirus's nucleic acid test is negative, but we should analyze its specific situation comprehensively.

What does novel coronavirus's negative mean? Novel coronavirus negative means that no nucleic acid is found in nucleic acid detection, which is the most important diagnostic basis for the diagnosis of novel coronavirus infection. The main way is to take nasopharyngeal swab, sputum, lower respiratory secretions, blood or feces for nucleic acid detection to see if there is any nucleic acid. If the nucleic acid is positive, it can be diagnosed as a clinically confirmed case. If 1 time nucleic acid test is negative, it cannot be ruled out that COVID-19 is infected. It is necessary to take secretions from different parts to check nucleic acid, which usually takes 4-6 times. The highly suspected patient's nucleic acid test is still negative and should be diagnosed as a clinically diagnosed case or a suspected case. If the asymptomatic infected person has no symptoms, but the nucleic acid test is positive, it should also be regarded as a confirmed case.

What does negative nucleic acid test mean for a new type of coronary pneumonia? If the nucleic acid test is negative, it means that the patient is not infected with coronavirus and the result is normal. However, due to the possibility of false negative in nucleic acid detection, that is, when patients are infected with coronavirus, nucleic acid detection may not be detected. Even if the test is negative, other tests such as blood routine and chest CT should be improved. If the blood routine and chest CT are normal, there will be no novel coronavirus if the patient is considered. If there are problems with blood routine and chest CT, or support coronavirus pneumonia infection, coronavirus nucleic acid should be detected several times to determine whether it is false negative.