What is the principle of Nocicnatron and why do you need to take it for life?

Nosey sodium injection is an antisense oligonucleotide (ASO), which was developed by the proprietary antisense technology of ion is Company. It is designed to treat SMA caused by SMN protein deficiency caused by mutation or deletion of SMN 1 gene (located on chromosome 5q). Noxinasone sodium injection can change the splicing of SMN2 pre-mRNA, thus increasing the production of full-length SMN protein.

ASO is a synthetic short nucleotide chain, which can be used to selectively bind to target RNA and regulate gene expression. Through the use of this technology, it has been proved that Nosey sodium injection can increase the number of full-length SMN protein in SMA patients.

Noxii sodium injection is administered by intrathecal injection, and the drug is directly delivered to cerebrospinal fluid (CSF) around the spinal cord, which is the site of motor neuron degeneration caused by insufficient SMN protein level in SMA patients.

Nosey sodium injection is a therapeutic drug for spinal muscular dystrophy developed by Biogen Idec Ltd, which was first approved in the United States on 20 16 65438.

From April 28th, 2009 to April 28th, 2065438, Noxii sodium injection was marketed in China, which was used to treat 5qSMA, becoming the first drug to treat SMA in China.

20 16 16 On February 23rd, Nocina sodium injection was approved for the first time in the United States, and it is the first precise targeted therapy drug for SMA in the world. Subsequently, it was approved for the treatment of SMA in the European Union, Brazil, Japan, South Korea, Canada and other countries.

From April 28th, 2009 to April 28th, 2065438, Noxii sodium injection was marketed in China, which was used to treat 5qSMA, becoming the first drug to treat SMA in China.

Nusinessen is the first approved SMA therapeutic drug in the world. As of June 30, 2020, Nusinessen has been approved in 50 countries and regions around the world and reimbursed in more than 40 countries and regions.

According to experts, Noxii sodium injection is an antisense nucleotide therapy drug for 5q spinal muscular atrophy in infants, children and adults, and it is also the first imported drug approved for the treatment of spinal muscular atrophy in China. Doctors administer drugs to patients by intrathecal injection (injecting drugs into the body through lumbar puncture).

Children should take medicine as soon as possible after diagnosis:

You need six shots in the first year and four shots in the first two months. After that, you need to inject 1 needle every 4 months.

In Wu Shuo, some children have recovered their athletic ability to some extent after injecting drugs. Nuo Nuo, a 2-year-old 1 1 month-old child in Hunan, started to inject this medicine in May this year, and has injected it four times so far. After treatment, Nuo Nuo's athletic ability recovered well.

Reference to the above content: Baidu Encyclopedia-Nosinasheng