What problems will space immigrants face?

1. At least quantum computers are used to support the navigation of the spacecraft, including channel, speed, asteroid avoidance, life support system, etc. Ordinary computers are not fast enough.

2. Spacecraft, including antimatter energy or at least some energy higher than nuclear energy, can resist the impact of cosmic dust, absolute zero, thousands of degrees of high temperature and so on, and have a full set of life support systems and many other problems.

3. A livable planet. Without it, the spacecraft will be big enough to carry enough materials to make a dome.

Few steps, it's hard.