What is the historical reason for the distribution of whites in the United States?

After the opening of the new route, Spain, Portugal, Britain, France and other western European countries successively established colonies. Colonial activities in Europe made native American Indians enslaved and slaughtered, or infected with European infectious diseases such as influenza and smallpox and died in large numbers (Indians were isolated from the world at that time and had no resistance to these diseases). In Europe, many people came to live and settle in colonies under the pressure of life or taking refuge. Later, American colonies became independent and American countries appeared. Now the white people in America are the descendants of those people.