Can I resign from the company after working in Thailand and obtaining a work permit?

As far as I know, I can resign. If you resign, your work permit will be invalid, because the company will go to the immigration office to cancel your work permit.

If you want to work in another company after resigning, you must apply for a new work permit. One thing to note is to do a good job in the relationship with the company. For example, if you work in a company, you find another better job, so you have to resign. You have to communicate with the company where you want to work and your company in advance, and then your company will take you to cancel your work permit, and then you will apply for a new work permit in the company where you want to work. I heard a friend say that a man found a better job while working in the company, and then had an argument with the company to leave. Later, the original company didn't want to take him to cancel his work permit or something, which caused a lot of trouble.